A DNA Aptamer Targeting Galectin-1 as a Novel Immunotherapeutic Strategy for Lung Cancer

• Main Authors: Yao-Tsung Tsai (Author), Chen-Hsien Liang (Author), Jin-Hsuan Yu (Author), Kuan-Chih Huang (Author), Chia-Hao Tung (Author), Jia-En Wu (Author), Yi-Ying Wu (Author), Chih-Hsien Chang (Author), Tse-Ming Hong (Author), Yuh-Ling Chen (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Galectin-1 (Gal-1) is a pleiotropic homodimeric β-galactoside-binding protein with a single carbohydrate recognition domain. It has been implicated in several biological processes that are important during tumor progression. Several lines of evidence have indicated that Gal-1 is involved in cancer i...