Pharmacogenomic polygenic risk score for clopidogrel responsiveness among Caribbean Hispanics: A candidate gene approach

• Main Authors: Jorge Duconge (Author), Ednalise Santiago (Author), Dagmar F. Hernandez‐Suarez (Author), Mariangeli Moneró (Author), Andrés López‐Reyes (Author), Marines Rosario (Author), Jessicca Y. Renta (Author), Pablo González (Author), Laura Ileana Fernández‐Morales (Author), Luis Antonio Vélez‐Figueroa (Author), Orlando Arce (Author), Frances Marín‐Maldonado (Author), Héctor Nuñez (Author), Kyle Melin (Author), Stuart A. Scott (Author), Gualberto Ruaño (Author)
• Format: Book
• Published: Wiley, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This multicenter clinical study was aimed at conducting a targeted pharmacogenomic association analysis of residual on‐clopidogrel platelet reactivity in 474 Caribbean Hispanic patients. Platelet reactivity was measured using the VerifyNow P2Y12 assay and clopidogrel resistance was defined...