FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest

• Main Authors: Susanna Søberg (Author), Emilie S. Andersen (Author), Niels B. Dalgaard (Author), Ida Jarlhelt (Author), Nina L. Hansen (Author), Nina Hoffmann (Author), Tina Vilsbøll (Author), Anne Chenchar (Author), Michal Jensen (Author), Trisha J. Grevengoed (Author), Sam A.J. Trammell (Author), Filip K. Knop (Author), Matthew P. Gillum (Author)
• Format: Book
• Published: Elsevier, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Excessive alcohol consumption is a leading cause of global morbidity and mortality. However, knowledge of the biological factors that influence ad libitum alcohol intake may be incomplete. Two large studies recently linked variants in the KLB locus with levels of alcohol intake in humans....