Three Siblings with Idiopathic Hypogonadotropic Hypogonadism in a Nonconsanguineous Family: A Novel KISS1R/GPR54 Loss-of-Function Mutation

• मुख्य लेखकों: Özlem Nalbantoğlu (लेखक), Gülçin Arslan (लेखक), Özge Köprülü (लेखक), Filiz Hazan (लेखक), Semra Gürsoy (लेखक), Behzat Özkan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Galenos Yayincilik, 2019-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Idiopathic hypogonadotropic hypogonadism (IHH) is a rare disease caused by defects in the secretion of gonadotropin releasing hormone (GnRH) or the action of GnRH on the pituitary gonadotrophes. KISS1R is one of the genes which, when mutated, cause IHH and mutations of this gene are responsible for...