Supplemental Ferulic Acid Inhibits Total Body Irradiation-Mediated Bone Marrow Damage, Bone Mass Loss, Stem Cell Senescence, and Hematopoietic Defect in Mice by Enhancing Antioxidant Defense Systems

• Главные авторы: Sajeev Wagle (Автор), Hyun-Jaung Sim (Автор), Govinda Bhattarai (Автор), Ki-Choon Choi (Автор), Sung-Ho Kook (Автор), Jeong-Chae Lee (Автор), Young-Mi Jeon (Автор)
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• Опубликовано: MDPI AG, 2021-07-01T00:00:00Z.
• Предметы: article
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While total body irradiation (TBI) is an everlasting curative therapy, the irradiation can cause long-term bone marrow (BM) injuries, along with senescence of hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) via reactive oxygen species (ROS)-induced oxidative damages. Thus, ameliora...