Compatibility of Caco-2 cells with Simulated Intestinal Fluid-Predicting Permeability

• Váldodahkkit: Erin Seonaid Campbell (Dahkki), Hannah Batchelor (Dahkki), James Matthew Butler (Dahkki), Ibrahim Khadra (Dahkki), Nena Minstry (Dahkki), Konstantinos Stamatopoulos (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: University of Huddersfield Press, 2023-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The Caco-2 cell model is considered the gold standard when analysing drug permeability and risk-assessing bioavailability. The use of Simulated Intestinal Fluid (SIF) as a tool in the Caco-2 models is beneficial as this generates a more physiologically relevant model. Existing work using biorelevant...