Rhynchophylline Regulates Calcium Homeostasis by Antagonizing Ryanodine Receptor 2 Phosphorylation to Improve Diabetic Cardiomyopathy

• Main Authors: Jiao Liu (Author), Yating Zhao (Author), Yufang Zhu (Author), Yan Wang (Author), Xiaoshuang Liu (Author), Xiaobo Nie (Author), Jing Zhao (Author), Wei Wang (Author), Jie Cheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes that can lead to heart failure and death, for which there is no effective treatment. Rhynchophylline (Rhy) is the main effective component of the Chinese herbal medicine Uncaria rhynchophylla, which mainly acts on the cardiovascular...