DTMP-prime: A deep transformer-based model for predicting prime editing efficiency and PegRNA activity

Prime editors are CRISPR-based genome engineering tools with significant potential for rectifying patient mutations. However, their usage requires experimental optimization of the prime editing guide RNA (PegRNA) to achieve high editing efficiency. This paper introduces the deep transformer-based mo...

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Main Authors: Roghayyeh Alipanahi (Author), Leila Safari (Author), Alireza Khanteymoori (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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