Febrile Urinary Tract Infections in Children: The Role of High Mobility Group Box-1

• Main Authors: Roberto Chimenz (Author), Valeria Chirico (Author), Caterina Cuppari (Author), Alessia Sallemi (Author), Davide Cardile (Author), Sergio Baldari (Author), Giorgio Ascenti (Author), Paolo Monardo (Author), Antonio Lacquaniti (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Differentiating between febrile lower urinary tract infection (LUTI) and acute pyelonephritis (APN) is crucial for prompt clinical management. We investigated whether the high mobility group box-1 (HMGB1) could be a useful biomarker in differentiating between LUTI or APN. Methods: We enr...