Neuropsychotoxicity of Abused Drugs: Involvement of Matrix Metalloproteinase-2 and -9 and Tissue Inhibitor of Matrix Metalloproteinase-2 in Methamphetamine-Induced Behavioral Sensitization and Reward in Rodents

Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) function to remodel the pericellular environment. We have investigated the role of the MMP/ TIMP system in methamphetamine (METH) dependence in rodents, in which the remodeling of neural circuits may be crucial. Repeated METH treatment in...

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Hoofdauteurs: Hiroyuki Mizoguchi (Auteur), Kiyofumi Yamada (Auteur), Toshitaka Nabeshima (Auteur)
Formaat: Boek
Gepubliceerd in: Elsevier, 2008-01-01T00:00:00Z.
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