Concentration-Dependent Inhibitory Effect of Irbesartan on Renal Uric Acid Transporters

• Main Authors: Makiko Nakamura (Author), Naohiko Anzai (Author), Promsuk Jutabha (Author), Hiroyuki Sato (Author), Hiroyuki Sakurai (Author), Kimiyoshi Ichida (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperuricemia is currently recognized as a risk factor for cardiovascular diseases. It has been reported that the angiotensin II-receptor blocker (ARB) losartan decreases serum uric acid level. In this study, the effects of another ARB, irbesartan, on [14C]uric acid-transport activity of renal uric...