Isolating the role of elevated Phlda2 in asymmetric late fetal growth restriction in mice

• Egile Nagusiak: Simon J. Tunster (Egilea), Mathew Van De Pette (Egilea), Rosalind M. John (Egilea)
• Formatua: Liburua
• Argitaratua: The Company of Biologists, 2014-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Pleckstrin homology-like domain family A member 2 (PHLDA2) is a maternally expressed imprinted gene whose elevated expression has been linked to fetal growth restriction in a number of human studies. In mice, Phlda2 negatively regulates placental growth and limits the accumulation of placental glyco...