Diagnostic accuracy of PCR in gambiense sleeping sickness diagnosis, staging and post-treatment follow-up: a 2-year longitudinal study.

• Main Authors: Stijn Deborggraeve (Author), Veerle Lejon (Author), Rosine Ali Ekangu (Author), Dieudonné Mumba Ngoyi (Author), Patient Pati Pyana (Author), Médard Ilunga (Author), Jean Pierre Mulunda (Author), Philippe Büscher (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The polymerase chain reaction (PCR) has been proposed for diagnosis, staging and post-treatment follow-up of sleeping sickness but no large-scale clinical evaluations of its diagnostic accuracy have taken place yet. METHODOLOGY/PRINCIPAL FINDINGS:An 18S ribosomal RNA gene targeting PCR wa...