Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats

• Autori principali: Tayyaba Afsar (Autore), Suhail Razak (Autore), Khalid Mujasam Batoo (Autore), Muhammad Rashid Khan (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2017-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background The use of doxorubicin (DOX) an anthracycline antineoplastic agent is withdrawn due to its cardio-toxic side effects. Oxidative stress has been recognized as the primary cause of DOX induced cardiotoxicity. We have investigated whether polyphenol rich ethyl acetate extract of Aca...