A novel DNA aptamer targeting lung cancer stem cells exerts a therapeutic effect by binding and neutralizing Annexin A2

• Main Authors: Yi-Ying Wu (Author), I-Shan Hsieh (Author), Chia-Hao Tung (Author), Chen-Hsun Weng (Author), Jia-En Wu (Author), Jau-Song Yu (Author), Tse-Ming Hong (Author), Yuh-Ling Chen (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer remains one of the leading causes of death worldwide. Cancer stem cells (CSCs) are the underlying reason for tumor recurrence, progression, and therapeutic resistance. Aptamers are synthetic single-stranded oligonucleotides that can specifically bind to various molecular targets. Here, we aim...