Comprehensive analysis of hub genes associated with cisplatin-resistance in ovarian cancer and screening of therapeutic drugs through bioinformatics and experimental validation

• Main Authors: Yunshan Zhu (Author), Xuehong Chen (Author), Rongrong Tang (Author), Guangxiao Li (Author), Jianhua Yang (Author), Shihao Hong (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background To identify key genes associated with cisplatin resistance in ovarian cancer, a comprehensive analysis was conducted on three datasets from the GEO database and through experimental validation. Methods Gene expression profiles were retrieved from the GEO database. DEGs were ident...