Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours

• Main Authors: Olga Bugaeva (Author), Pilvi Maliniemi (Author), Wenche S. Prestvik (Author), Eeva Leivo (Author), Nicolas Kluger (Author), Alexander Salava (Author), Sanna Virtanen (Author), Kirsi Jäntti (Author), Olli Saksela (Author), Kaisa Lehti (Author), Paula Kujala (Author), Kaj Krohn (Author), Annamari Ranki (Author)
• Format: Book
• Published: Medical Journals Sweden, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melanoma is a highly metastatic tumour originating from neural crest-derived melanocytes. The aim of this study was to analyse the expression of neuron navigator 3 (NAV3) in relation to membrane type-1 matrix metalloproteinase MMP14, a major regulator of invasion, in 40 primary melanomas, 15 benign...