Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia

• Main Authors: David Saceda-Corralo (Author), Daniel Ortega-Quijano (Author), Gloria Muñoz-Martín (Author), Óscar M. Moreno-Arrones (Author), Cristina Pindado-Ortega (Author), Tuntas Rayinda (Author), Ana Melián-Olivera (Author), Carlos Azcárraga-Llobet (Author), Patricia Burgos-Blasco (Author), María Elena Castañeda-Bermúdez (Author), Francisco J. del Castillo (Author), Sergio Vañó-Galván (Author)
• Format: Book
• Published: Medical Journals Sweden, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pathogenesis of frontal fibrosing alopecia has been linked to specific genetic variants. CYP1B1 codes for a component of the cytochrome p450 machinery that is involved in the metabolism of xenobiotic oestrogens. The study of the prevalence of polymorphisms in this gene may help to understand the...