A randomized, controlled Phase 1b trial of the Sm-TSP-2 Vaccine for intestinal schistosomiasis in healthy Brazilian adults living in an endemic area.

• Päätekijät: David J Diemert (Tekijä), Rodrigo Correa-Oliveira (Tekijä), Carlo Geraldo Fraga (Tekijä), Frederico Talles (Tekijä), Marcella Rezende Silva (Tekijä), Shital M Patel (Tekijä), Shirley Galbiati (Tekijä), Jessie K Kennedy (Tekijä), Jordan S Lundeen (Tekijä), Maria Flavia Gazzinelli (Tekijä), Guangzhao Li (Tekijä), Lara Hoeweler (Tekijä), Gregory A Deye (Tekijä), Maria Elena Bottazzi (Tekijä), Peter J Hotez (Tekijä), Hana M El Sahly (Tekijä), Wendy A Keitel (Tekijä), Jeffrey Bethony (Tekijä), Robert L Atmar (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Public Library of Science (PLoS), 2023-03-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

<h4>Background</h4>Recombinant Schistosoma mansoni Tetraspanin-2 formulated on Alhydrogel (Sm-TSP-2/Alhydrogel) is being developed to prevent intestinal and hepatic disease caused by S. mansoni. The tegumentary Sm-TSP-2 antigen was selected based on its unique recognition by cytophilic a...