Therapeutic Drug Monitoring of Second- and Third-Generation Antipsychotic Drugs-Influence of Smoking Behavior and Inflammation on Pharmacokinetics

• Main Authors: Nicole Moschny (Author), Gudrun Hefner (Author), Renate Grohmann (Author), Gabriel Eckermann (Author), Hannah B Maier (Author), Johanna Seifert (Author), Johannes Heck (Author), Flverly Francis (Author), Stefan Bleich (Author), Sermin Toto (Author), Catharina Meissner (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Both inflammation and smoking can influence a drug's pharmacokinetic properties, i.e., its liberation, absorption, distribution, metabolism, and elimination. Depending on, e.g., pharmacogenetics, these changes may alter treatment response or cause serious adverse drug reactions and are thus of...