Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data

• मुख्य लेखकों: Yitian Zhou (लेखक), Kohei Fujikura (लेखक), Souren Mkrtchian (लेखक), Volker M. Lauschke (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Up to half of all patients do not respond to pharmacological treatment as intended. A substantial fraction of these inter-individual differences is due to heritable factors and a growing number of associations between genetic variations and drug response phenotypes have been identified. Importantly,...