Polyvinylpyrrolidone-Coated Catheters Decrease Astrocyte Adhesion and Improve Flow/Pressure Performance in an Invitro Model of Hydrocephalus

• Main Authors: Leandro Castañeyra-Ruiz (Author), Seunghyun Lee (Author), Alvin Y. Chan (Author), Vaibhavi Shah (Author), Bianca Romero (Author), Jenna Ledbetter (Author), Michael Muhonen (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The leading cause of ventricular shunt failure in pediatric patients is proximal catheter occlusion. Here, we evaluate various types of shunt catheters to assess in vitro cellular adhesion and obstruction. The following four types of catheters were tested: (1) antibiotic- and barium-impregnated, (2)...