Paired comparisons of venetoclax concentration in cerebrospinal fluid, bone marrow, and plasma in acute leukemia patients

• Main Authors: Yuan Jian (Author), Feifei Han (Author), Ying Zhu (Author), Chuanying Geng (Author), Yanru Zhang (Author), Yin Wu (Author), Yun Leng (Author), Wenming Chen (Author), Zhuoling An (Author), Hong‐Hu Zhu (Author)
• Format: Book
• Published: Wiley, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Venetoclax, a small molecule inhibitor of BCL‐2, has demonstrated efficacy in treating acute leukemias and has been recommended as one of the first‐line anti‐leukemia therapies. Although venetoclax has been suggested to probably possess the ability to penetrate the central nervous system (C...