Polymeric Amorphous Solid Dispersions of Dasatinib: Formulation and Ecotoxicological Assessment

• Main Authors: Katarina Sokač (Author), Martina Miloloža (Author), Dajana Kučić Grgić (Author), Krunoslav Žižek (Author)
• Formato: Libro
• Publicado: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Dasatinib (DAS), a potent anticancer drug, has been subjected to formulation enhancements due to challenges such as significant first-pass metabolism, poor absorption, and limited oral bioavailability. To improve its release profile, DAS was embedded in a matrix of the hydrophilic polymer polyvinylp...