A functional role of Ephrin type-B receptor 6 (EPHB6) in T-cell acute lymphoblastic leukemia

• Main Authors: Mattia Colucci (Author), Nadia Trivieri (Author), Gandino Mencarelli (Author), Elisabetta De Santis (Author), Francesca Sansico (Author), Francesco Tamiro (Author), Alberto Visioli (Author), Chiara Barile (Author), Riccardo Pracella (Author), Giovanni Rossi (Author), Elena Binda (Author), Vincenzo Giambra (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract T-cell lymphoblastic acute leukemia (T-ALL) is an aggressive blood cancer, characterized by restricted cellular subsets with enriched leukemia initiating cells (LICs). Recently, Ephrin receptors (Eph) were described to be highly expressed in cancer stem cells. Here, using public RNA-Seq dat...