A transgenic zebrafish liver tumor model with inducible Myc expression reveals conserved Myc signatures with mammalian liver tumors

• Main Authors: Zhen Li (Author), Weiling Zheng (Author), Zhengyuan Wang (Author), Zhiqiang Zeng (Author), Huiqing Zhan (Author), Caixia Li (Author), Li Zhou (Author), Chuan Yan (Author), Jan M. Spitsbergen (Author), Zhiyuan Gong (Author)
• Format: Book
• Published: The Company of Biologists, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Myc is a pleiotropic transcription factor that is involved in many cellular activities relevant to carcinogenesis, including hepatocarcinogenesis. The zebrafish has been increasingly used to model human diseases and it is particularly valuable in helping to identify common and conserved mole...