Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34+ Cells

• Main Authors: Hui Xie (Author), Li Sun (Author), Liming Zhang (Author), Teng Liu (Author), Li Chen (Author), Aiqi Zhao (Author), Qian Lei (Author), Fei Gao (Author), Ping Zou (Author), Qiubai Li (Author), An-yuan Guo (Author), Zhichao Chen (Author), Hongxiang Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSCs) are known to support the characteristic properties of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow hematopoietic microenvironment. MSCs are used in coculture systems as a feeder layer for the ex vivo expansion of umbilical cord blood (CB) to increa...