High-fat diet enhanced retinal dehydrogenase activity, but suppressed retinol dehydrogenase activity in liver of rats

• Main Authors: Mian Zhang (Author), Can Liu (Author), Meng-yue Hu (Author), Ji Zhang (Author), Ping Xu (Author), Feng Li (Author), Ze-yu Zhong (Author), Li Liu (Author), Xiao-dong Liu (Author)
• Format: Book
• Published: Elsevier, 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Evidence has shown that hyperlipidemia is associated with retinoid dyshomeostasis. In liver, retinol is mainly oxidized to retinal by retinol dehydrogenases (RDHs) and alcohol dehydrogenases (ADHs), further converted to retinoic acid by retinal dehydrogenases (RALDHs). The aim of this study was to i...