Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet

• Asıl Yazarlar: Mahmoud Teaima (Yazar), Sandra Hababeh (Yazar), Mai Khanfar (Yazar), Fares Alanazi (Yazar), Doaa Alshora (Yazar), Mohammed El-Nabarawi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this research was to design orally disintegrating tablets with self-nanoemulsifying properties (T-SNEDDS) to improve the Pioglitazone solubility and dissolution rate. Three liquid self-nanoemulsifying systems (L-SNEDDS...