The gut microbiota-bile acid axis in cholestatic liver disease

• Main Authors: Dayan sun (Author), Chuanping Xie (Author), Yong Zhao (Author), Junmin Liao (Author), Shuangshuang Li (Author), Yanan Zhang (Author), Dingding Wang (Author), Kaiyun Hua (Author), Yichao Gu (Author), Jingbin Du (Author), Guoxian Huang (Author), Jinshi Huang (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cholestatic liver diseases (CLD) are characterized by impaired normal bile flow, culminating in excessive accumulation of toxic bile acids. The majority of patients with CLD ultimately progress to liver cirrhosis and hepatic failure, necessitating liver transplantation due to the lack of ef...