BF3·Et2O Catalysed 4-Aryl-3-phenyl-benzopyrones, Pro-SERMs, and Their Characterization

• Huvudskapare: Ambika Srivastava (Författare, medförfattare), Pooja Singh (Författare, medförfattare), Rajesh Kumar (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Hindawi Limited, 2015-01-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

We have synthesized the novel 4-(4-hydroxy-benzyl)-3-phenyl-chromen-2-one which is a precursor of SERMs with a smaller number of steps and good yield. Two methodologies for the synthesis have been worked out. Anhydrous BF3·Et2O catalyzed reaction was found to be selective for product formation while...