Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview

• Main Authors: Maria Bogdanova (Author), Arsenii Zabirnyk (Author), Anna Malashicheva (Author), Daria Semenova (Author), John-Peder Escobar Kvitting (Author), Mari-Liis Kaljusto (Author), Maria del Mar Perez (Author), Anna Kostareva (Author), Kåre-Olav Stensløkken (Author), Gareth J Sullivan (Author), Arkady Rutkovskiy (Author), Jarle Vaage (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve interstitial cells. To develop non-surgical treatments, the molecular and cell...