Uncovering the Cardioprotective Potential of Diacerein in Doxorubicin Cardiotoxicity: Mitigating Ferritinophagy-Mediated Ferroptosis via Upregulating NRF2/SLC7A11/GPX4 Axis

Uncovering the Cardioprotective Potential of Diacerein in Doxorubicin Cardiotoxicity: Mitigating Ferritinophagy-Mediated Ferroptosis via Upregulating NRF2/SLC7A11/GPX4 Axis

Doxorubicin (DOX)-induced cardiotoxicity (DIC) is a life-threatening clinical issue with limited preventive approaches, posing a substantial challenge to cancer survivors. The anthraquinone diacerein (DCN) exhibits significant anti-inflammatory, anti-proliferative, and antioxidant actions. Its benef...

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Main Authors: Rehab M. El-Gohary (Author), Asmaa H. Okasha (Author), Alaa H. Abd El-Azeem (Author), Muhammad T. Abdel Ghafar (Author), Sarah Ibrahim (Author), Islam I. Hegab (Author), Eman E. Farghal (Author), Soha Abdel Fattah Shalaby (Author), Ola A. Elshora (Author), Aisha E. ElMehy (Author), Amany Nagy Barakat (Author), Basma Saed Amer (Author), Fatma G. Sobeeh (Author), Gehan H. AboEl-Magd (Author), Asmaa A. Ghalwash (Author)
Format: Book
Published: MDPI AG, 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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