MicroRNA-15a/16 Regulates Apoptosis of Lung Epithelial Cells After Oxidative Stress

• Main Authors: Yong Cao (Author), Duo Zhang (Author), Hyung-Geun Moon (Author), Heedoo Lee (Author), Jeffrey A Haspel (Author), Kebin Hu (Author), Lixin Xie (Author), Yang Jin (Author)
• Format: Book
• Published: BMC, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Lung epithelial cell apoptosis is an important feature of hyperoxia-induced lung injury. The death receptor-associated extrinsic pathway and mitochondria-associated intrinsic pathway both mediate the development of lung epithelial cell apoptosis. Despite decades of research, molecular mecha...