MicroRNA-15a/16 Regulates Apoptosis of Lung Epithelial Cells After Oxidative Stress

• Autori principali: Yong Cao (Autore), Duo Zhang (Autore), Hyung-Geun Moon (Autore), Heedoo Lee (Autore), Jeffrey A Haspel (Autore), Kebin Hu (Autore), Lixin Xie (Autore), Yang Jin (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2016-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Lung epithelial cell apoptosis is an important feature of hyperoxia-induced lung injury. The death receptor-associated extrinsic pathway and mitochondria-associated intrinsic pathway both mediate the development of lung epithelial cell apoptosis. Despite decades of research, molecular mecha...