Epicardially Placed Bioengineered Cardiomyocyte Xenograft in Immune-Competent Rat Model of Heart Failure

• Main Authors: Ikeotunye Royal Chinyere (Author), Pierce Bradley (Author), Joshua Uhlorn (Author), Joshua Eason (Author), Saffie Mohran (Author), Giuliana G. Repetti (Author), Sherry Daugherty (Author), Jen Watson Koevary (Author), Steven Goldman (Author), Jordan J. Lancaster (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are under preclinical investigation as a cell-based therapy for heart failure post-myocardial infarction. In a previous study, tissue-engineered cardiac grafts were found to improve hosts' cardiac electrical and...