The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells

• Main Authors: Zuhier A. Awan (Author), Usama A. Fahmy (Author), Shaimaa M. Badr-Eldin (Author), Tarek S. Ibrahim (Author), Hani Z. Asfour (Author), Mohammed W. Al-Rabia (Author), Anas Alfarsi (Author), Nabil A. Alhakamy (Author), Wesam H. Abdulaal (Author), Hadeel Al Sadoun (Author), Nawal Helmi (Author), Ahmad O. Noor (Author), Filippo Caraci (Author), Diena M. Almasri (Author), Giuseppe Caruso (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Statins, including simvastatin (SMV), are commonly used for the control of hyperlipidaemia and have also proven therapeutic and preventative effects in cardiovascular diseases. Besides that, there is an emerging interest in their use as antineoplastic drugs as demonstrated by different studies showi...