Codon-Optimized P1A-Encoding DNA Vaccine: Toward a Therapeutic Vaccination against P815 Mastocytoma

DNA vaccine can be modified to increase protein production and modulate immune response. To enhance the efficiency of a P815 mastocytoma DNA vaccine, the P1A gene sequence was optimized by substituting specific codons with synonymous ones while modulating the number of CpG motifs. The P815A murine a...

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Main Authors: Alessandra Lopes (Author), Kevin Vanvarenberg (Author), Véronique Préat (Author), Gaëlle Vandermeulen (Author)
Format: Book
Published: Elsevier, 2017-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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