In the quest for new targets for pathogen eradication: the adenylosuccinate synthetase from the bacterium Helicobacter pylori

• Main Authors: Ante Bubić (Author), Natalia Mrnjavac (Author), Igor Stuparević (Author), Marta Łyczek (Author), Beata Wielgus-Kutrowska (Author), Agnieszka Bzowska (Author), Marija Luić (Author), Ivana Leščić Ašler (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adenylosuccinate synthetase (AdSS) is an enzyme at regulatory point of purine metabolism. In pathogenic organisms which utilise only the purine salvage pathway, AdSS asserts itself as a promising drug target. One of these organisms is Helicobacter pylori, a wide-spread human pathogen involved in the...