Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.
The parasitic protozoan Trypanosoma brucei causes Human African Trypanosomiasis and Nagana in other mammals. These diseases present a major socio-economic burden to large areas of sub-Saharan Africa. Current therapies involve complex and toxic regimens, which can lead to fatal side-effects. In addit...
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Main Authors: | Pieter C Steketee (Author), Isabel M Vincent (Author), Fiona Achcar (Author), Federica Giordani (Author), Dong-Hyun Kim (Author), Darren J Creek (Author), Yvonne Freund (Author), Robert Jacobs (Author), Kevin Rattigan (Author), David Horn (Author), Mark C Field (Author), Annette MacLeod (Author), Michael P Barrett (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2018-05-01T00:00:00Z.
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