Food and Sex-Related Impacts on the Pharmacokinetics of a Single-Dose of Ginsenoside Compound K in Healthy Subjects

• Main Authors: Lulu Chen (Author), Luping Zhou (Author), Yaqin Wang (Author), Guoping Yang (Author), Jie Huang (Author), Zhirong Tan (Author), Yicheng Wang (Author), Gan Zhou (Author), Jianwei Liao (Author), Dongsheng Ouyang (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background and Objectives: Ginsenoside compound K (CK) is a candidate drug for rheumatoid arthritis therapy. This clinical trial was designed to evaluate the effects of food and sex on the pharmacokinetics of CK and its metabolite 20(S)-protopanaxadiol (PPD).Methods: An open-label, single-center, tw...