Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity

• Үндсэн зохиолчид: Amanda Fernandes de Medeiros (Зохиогч), Izael de Sousa Costa (Зохиогч), Fabiana Maria Coimbra de Carvalho (Зохиогч), Sumika Kiyota (Зохиогч), Beatriz Blenda Pinheiro de Souza (Зохиогч), Daniel Nogoceke Sifuentes (Зохиогч), Raphael Paschoal Serquiz (Зохиогч), Bruna Leal Lima Maciel (Зохиогч), Adriana Ferreira Uchôa (Зохиогч), Elizeu Antunes dos Santos (Зохиогч), Ana Heloneida de Araújo Morais (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

A trypsin inhibitor isolated from tamarind seed (TTI) has satietogenic effects in animals, increasing the cholecystokinin (CCK) in eutrophy and reducing leptin in obesity. We purified TTI (pTTI), characterised, and observed its effect upon CCK and leptin in obese Wistar rats. By HPLC, and after ampl...