Impaired mRNA Expression of the Migration Related Chemokine Receptor CXCR4 in Mesenchymal Stem Cells of COPD Patients

• Main Authors: K. Karagiannis (Author), A. Proklou (Author), E. Tsitoura (Author), I. Lasithiotaki (Author), C. Kalpadaki (Author), D. Moraitaki (Author), I. Sperelakis (Author), G. Kontakis (Author), K. M. Antoniou (Author), N. Tzanakis (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Defective tissue repair and remodeling are main aspects of Chronic Obstructive Pulmonary Disease (COPD) pathophysiology. Bone marrow mesenchymal stem cells (BM-MSCs) have been implicated in this direction, as their functional impairment and recruitment could possibly contribute to disease developmen...