Helminth coinfection does not affect therapeutic effect of a DNA vaccine in mice harboring tuberculosis.

• Main Authors: Fabiani G Frantz (Author), Rogério S Rosada (Author), Camila Peres-Buzalaf (Author), Franciele R T Perusso (Author), Vanderlei Rodrigues (Author), Simone G Ramos (Author), Steven L Kunkel (Author), Célio L Silva (Author), Lúcia H Faccioli (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Helminthiasis and tuberculosis (TB) coincide geographically and there is much interest in exploring how concurrent worm infections might alter immune responses against bacilli and might necessitate altered therapeutic approaches. A DNA vaccine that codifies heat shock protein Hsp65 from...