Renoprotective Effects of Melatonin in Young Spontaneously Hypertensive Rats with L-NAME

• Main Authors: Ming-Chou Cheng (Author), Ting-Hsin Wu (Author), Li-Tung Huang (Author), You-Lin Tain (Author)
• Format: Book
• Published: Elsevier, 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nitric oxide (NO) deficiency occurs in humans and animals with hypertension and chronic kidney disease (CKD). An inhibitor of NO synthase, NG-nitro-l-arginine methyl ester (L-NAME) exacerbates kidney damage in the adult spontaneously hypertensive rat (SHR). We examined whether L-NAME exacerbated hyp...