Optimization of the Solvent and In Vivo Administration Route of Auranofin in a Syngeneic Non-Small Cell Lung Cancer and Glioblastoma Mouse Model

• मुख्य लेखकों: Laurie Freire Boullosa (लेखक), Jinthe Van Loenhout (लेखक), Christophe Hermans (लेखक), Ho Wa Lau (लेखक), Céline Merlin (लेखक), Elly Marcq (लेखक), Farnaz Sedigheh Takhsha (लेखक), Wim Martinet (लेखक), Guido R. Y. De Meyer (लेखक), Filip Lardon (लेखक), Evelien L. J. Smits (लेखक), Christophe Deben (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The antineoplastic activity of the thioredoxin reductase 1 (TrxR) inhibitor, auranofin (AF), has already been investigated in various cancer mouse models as a single drug, or in combination with other molecules. However, there are inconsistencies in the literature on the solvent, dose and administra...