Strategies to improve drug penetration into tumor microenvironment by nanoparticles: Focus on nanozymes

• Main Authors: Elaheh Dalir Abdolahinia (Author), Marziyeh Fathi (Author), Zahra Pirdel (Author), Samira Jafari (Author), Mohammad Samiei (Author), Khosro Adibkia (Author), Farshid Sefat (Author), Solmaz Maleki Dizaj (Author), Simin Sharifi (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Solid tumors are composed of a complex organ-like structure, comprising tumor, immune and stromal cells, extracellular matrix (ECM), and blood vessels. Tumor microenvironments (TME), including ECM, make up the majority of the tumor and greatly influence the intratumor signaling, metabolism, and oxyg...