Gingerol-Enriched Ginger Supplementation Mitigates Neuropathic Pain via Mitigating Intestinal Permeability and Neuroinflammation: Gut-Brain Connection

• Main Authors: Chwan-Li Shen (Author), Rui Wang (Author), Vadim Yakhnitsa (Author), Julianna Maria Santos (Author), Carina Watson (Author), Takaki Kiritoshi (Author), Guangchen Ji (Author), Abdul Naji Hamood (Author), Volker Neugebauer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Emerging evidence suggests an important role of the gut-brain axis in the development of neuropathic pain (NP). We investigated the effects of gingerol-enriched ginger (GEG) on pain behaviors, as well as mRNA expressions of inflammation via tight junction proteins in GI tissues (colon) a...