Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities

• Main Authors: Sveva Pelliccia (Author), Yu-Hsuan Wu (Author), Antonio Coluccia (Author), Giuseppe La Regina (Author), Chin-Kai Tseng (Author), Valeria Famiglini (Author), Domiziana Masci (Author), John Hiscott (Author), Jin-Ching Lee (Author), Romano Silvestri (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV) is the leading mosquito-transmitted viral infection in the world. With more than 390 million new infections annually, and up to 1 million clinical cases with severe disease manifestations, there continues to be a need to develop new antiviral agents against dengue infection. In a...