Dextromethorphan improved cyclosporine-induced depression in mice model of despair

• Egile Nagusiak: Azadeh Mesripour (Egilea), Mojgan Golbidi (Egilea), Valiollah Hajhashemi (Egilea)
• Formatua: Liburua
• Argitaratua: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background and purpose: Cyclosporine (Cyc) is a calcineurin inhibitor used in immunosuppressive therapy that may cause psychological problems such as depression. Previous investigations have shown the positive antidepressant effects of dextromethorphan (Dxt). Therefore, the aim of this study was the...