Predicting the correct dose in children: Role of computational Pediatric Physiological‐based pharmacokinetics modeling tools

• Main Authors: Xu Zhou (Author), Jiening Dun (Author), Xiao Chen (Author), Bai Xiang (Author), Yunjie Dang (Author), Deying Cao (Author)
• Format: Book
• Published: Wiley, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The pharmacokinetics (PKs) and safety of medications in particular groups can be predicted using the physiologically‐based pharmacokinetic (PBPK) model. Using the PBPK model may enable safe pediatric clinical trials and speed up the process of new drug research and development, especially f...